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Prehospital Emergency Pharmacology, 8e (Bledsoe/Clayden)
Chapter 2 Pharmacokinetics and Pharmacodynamics
1) Two major divisions of pharmacology are:
A) Pharmacokinetics and pharmacodynamics.
B) Pharmacognosy and biotransformation.
C) Active transport and diffusion.
D) Biotransformation and elimination.
Answer: A
Explanation: A) Pharmacokinetics and pharmacodynamics are the two major divisions of
pharmacology.
B) Pharmacognosy refers to the broad study of natural and synthetic drugs and biotransformation
is a function of pharmacokinetics.
C) Active transport and diffusion explain how a medication moves.
D) Biotransformation and elimination is a function of pharmacokinetics.
Page Ref: 26
2) Which of the following factors is NOT a component of pharmacokinetics?
A) Absorption
B) Distribution
C) Biotransformation
D) Binding
Answer: D
Explanation: A) Absorption explains the movement of a medication into the system.
B) Distribution is how the medication travels to target tissues or organs.
C) Biotransformation is how a medication is broken down in the system.
D) Binding is a component of pharmacodynamics.
Page Ref: 26
3) Drug A requires the use of adenosine triphosphate (ATP) in order to move into the cellular
membrane. This type of diffusion is known as:
A) Elimination.
B) Active transport.
C) Facilitated.
D) Osmosis.
Answer: B
Explanation: A) Elimination is the removal of a drug from the body.
B) Active transport involves the use of energy, such as ATP to move a substance through a
membrane that otherwise would not be able to penetrate.
C) Facilitated diffusion requires the use of a helper protein (such as insulin with glucose) to
cause a change in the cellular membrane allowing entry of the substance.
D) Osmosis is a passive process involving the movement of water.
Page Ref: 26