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Test Bank (Download Now) For Brody’s Human Pharmacology 6th Edition by Wecker ISBN: 9780323476522

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Test Bank (Download Now) For Brody’s Human Pharmacology 6th Edition by Wecker ISBN: 9780323476522

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1. Binding of a drug to its target most often:
A. Involves covalent binding between the target and the drug.
B. Involves more than one type of weak bond between the drug
and its target.
C. Requires long-lasting stable bonds between the drug and its
target.
D. Has a similar affinity for the several stereoisomers of the
drug.
E. Is characterized by high KD values.
2. A patient was being maintained on a β-adrenergic receptor antagonist
to control hypertension. The continuous exposure of receptor to
this antagonist can:
A. Result in supersensitivity.
B. Desensitize the receptor.
C. Produce tachyphylaxis.
D. Cause down regulation of the receptor.
E. B and C are correct.
3. Which of the following statements regarding drugs’ action and cell
surface receptors is not correct?
A. By acting on receptors, drugs can enhance, diminish, or block
generation or transmission of signals.
B. The KD of drug binding to receptors can vary widely.
C. Agonist drugs are highly specific for each subtype of receptor in
various classes of receptors.
D. More than one drug molecule may be required to bind to a
receptor and elicit a response.
E. Receptors are frequently glycosylated.
4. Which of the following processes are involved in intracellular signaling
cascades?
A. Tyrosine phosphorylation.
B. Receptor association with and stimulation of G proteins.
C. Formation of second messengers, such as cAMP.
D. Mobilization of Ca2+
from the endoplasmic reticulum.
E. All of the above.
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